{"id":778,"date":"2020-02-28T15:09:51","date_gmt":"2020-02-28T15:09:51","guid":{"rendered":"https:\/\/www.dossiermanager.it\/?p=778"},"modified":"2024-11-12T11:20:00","modified_gmt":"2024-11-12T10:20:00","slug":"titanium-dioxide-e-titanium-dioxidenano-ultime-novita-e-qualche-riepilogo","status":"publish","type":"post","link":"https:\/\/www.dossiermanager.it\/en\/2020\/02\/28\/titanium-dioxide-e-titanium-dioxidenano-ultime-novita-e-qualche-riepilogo\/","title":{"rendered":"TITANIUM DIOXIDE and TITANIUM DIOXIDE(NANO), last news and some summary"},"content":{"rendered":"<div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-margin-top:-50px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_1 1_1 fusion-one-full fusion-column-first fusion-column-last\" style=\"--awb-bg-size:cover;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-column-wrapper-legacy\"><div class=\"fusion-text fusion-text-1\"><p>TITANIUM DIOXIDE (CAS 13463-67-7) is a substance used in various fields, from cosmetics to paints.<\/p>\n<p>Here are some important steps of investigation and proposed classification that the substance has undergone over the years by ECHA, European Chemicals Agency, up to the definition of a few days ago.<\/p>\n<p>Nel settembre 2017 l\u2019ECHA ha proposto di classificare il Titanium dioxide come cancerogeno di categoria 2 per inalazione;<br \/>\nnel settembre 2019 la Commissione europea ha proseguito con tale proposta di classificazione ed infine ha adottato il Regolamento delegato (UE) 2020\/217 della Commissione del 4 ottobre 2019, pubblicato nella GUUE n. 44 del 18\/2\/2020, contenente il XIV ATP (adattamento al progresso tecnico)che di fatto ha modificato il Reg.1272\/2008 (CLP), inserendo per le forme di polvere inalabili di TITANIUM DIOXIDE la controversa classificazione H315, ovvero cancerogeno di classe 2 per inalazione. Questa classificazione si applica unicamente alla sostanza TiO2 in polvere contenente \u22651 % di particelle con diametro aerodinamico \u226410 \u03bcm e alle miscele sotto forma di polveri contenenti \u22651 % di particelle di TiO2 sotto forma di, o incorporato in, particelle con diametro aerodinamico \u226410 \u03bcm. Le modifiche del CLP nell&#8217;allegato VI entreranno in vigore il 9 marzo 2020 e le classificazioni armonizzate si applicheranno 18 mesi dopo<\/p>\n<p>L\u2019Industria cosmetica intende difendere l\u2019utilizzo di questo ingrediente e nei primi mesi di quest\u2019anno saranno consegnati a SCCS tutti i dati necessari per garantirne la sicurezza. L\u2019Industria ha intenzione di difenderlo anche nei prodotti che potrebbero comportare un\u2019esposizione nei polmoni, ma non si sa se questa difesa andr\u00e0 a buon fine.<\/p>\n<p>Article 32 of Regulation 1223\/2009 on cosmetic products prohibits the use of substances classified as carcinogenic, mutagenic or toxic for reproduction (CMR), category 1A, 1B and 2, according to the CLP regulation.<\/p>\n<p>However, there are cases where the use of CMR substances is allowed following specific evaluations by SCCS attesting to their safety for use in cosmetics.<\/p>\n<p>Titanium dioxide is currently used in cosmetic products as a colorant (therefore present in All.IV of Reg. 1223 at no. 143) and as a UV filter (therefore present in All.VI of Reg. 1223 at no. 27, maximum concentration of use 25%).<\/p>\n<p class=\"translation-block\">In addition, the use of TiO<sub>2<\/sub> (nano) as a UV filter has also been admitted (All.VI of Reg.1223 at no.27bis); in this case, however, the characteristics that the nanomaterials can have are specified. In accordance with what was established by SCCS in the Final opinion SCCS\/1580\/16 \"Opinion on Titanium Dioxide (nano form) coated with Cetyl Phosphate, Manganese Dioxide or Triethoxycaprylylsilane as UV-filter in dermally applied cosmetics\", Regulation (EU) 2019\/1857 authorizes the use of three new forms of Titanium Dioxide (nano) coated<\/p>\n<ul>\n<li>or with silica conc.max. 16% and cetylphosphate conc. max. 6%;<\/li>\n<li>or with aluminum oxide conc. max. 3% and triethoxyprilysilane conc. max. 9%.<\/li>\n<li>with aluminum oxide conc. max. 7% and manganese dioxide conc. max. 0.7%. With this specific coating, since under reasonably foreseeable conditions of use consumers may apply certain facial products, such as sunscreens intended for facial application, to their lips, the specific warning \"Not for use on the lips\" will need to be stated.<\/li>\n<\/ul>\n<p>On the other hand, the use of Titanium Dioxide in nano form is not allowed in applications that could lead to exposure of consumers' lungs to titanium dioxide nanoparticles by inhalation (such as powders or sprays). In fact, Final Opinion SCCS\/1583\/17 \"Opinion on Titanium Dioxide (nano form) as UV-Filter in sprays\" specified that the data provided are insufficient to assess the safety of Titanium Dioxide in nano form in sun and personal care products when used in spray form, products that could result in end-user lung exposure by inhalation. For SCCS, the data dossier provided only describes exposure studies conducted with water-based spray products with low alcohol content, which currently represent about 80% of spray sunscreen products on the EU market. For non-water-based formulations or formulations containing alcohol in % greater than 10%, which may currently account for about 20% of sunscreen spray products on the EU market, no exposure data were submitted, and therefore the assessment cannot be performed.<\/p>\n<\/div><div class=\"fusion-sep-clear\"><\/div><div class=\"fusion-separator fusion-clearfix\" style=\"float:left;margin-bottom:50px;width:100%;max-width:100px;\"><div class=\"fusion-separator-border sep-single sep-solid\" style=\"--awb-height:20px;--awb-amount:20px;--awb-sep-color:#bf0208;border-color:#bf0208;border-top-width:4px;\"><\/div><\/div><div class=\"fusion-sep-clear\"><\/div><div class=\"fusion-tabs fusion-tabs-1 classic nav-is-justified awb-tabs-transition awb-tabs-transition-fade horizontal-tabs icon-position-left mobile-mode-accordion\" 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id=\"fusion-tab-c65f104e9c46d3ad741\" href=\"#tab-c65f104e9c46d3ad741\"><h4 class=\"fusion-tab-heading\">Tutorial<\/h4><\/a><\/li><li  role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-afa7445234f2cecb6b7\" aria-selected=\"false\" tabindex=\"-1\" id=\"fusion-tab-afa7445234f2cecb6b7\" href=\"#tab-afa7445234f2cecb6b7\"><h4 class=\"fusion-tab-heading\">Regulatory Answers<\/h4><\/a><\/li><li  role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-034ebdb30b6509ab6da\" aria-selected=\"false\" tabindex=\"-1\" id=\"fusion-tab-034ebdb30b6509ab6da\" href=\"#tab-034ebdb30b6509ab6da\"><h4 class=\"fusion-tab-heading\">Release Notes<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-content\"><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs nav-justified\" role=\"tablist\" aria-orientation=\"horizontal\"><li class=\"active\" role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" 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href=\"https:\/\/www.dossiermanager.it\/en\/2025\/10\/28\/consultazione-pubblica-octocrylene\/\">Consultazione pubblica Octocrylen<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2025\/10\/13\/titanium-dioxide-annullata-la-classificazione-come-carc-2-h315\/\">Titanium Dioxide, annullata la classificazione come CARC.2 (H315)<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2025\/09\/22\/aggiornamento-del-manuale-dei-cosmetici-borderline-versione-5-5\/\">Aggiornamento del Manuale dei cosmetici Borderline: versione 5.5<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2025\/09\/16\/la-commissione-europea-porta-la-francia-davanti-alla-corte-di-giustizia-per-luso-del-logo-triman\/\">La Commissione Europea porta la Francia davanti alla Corte di Giustizia per l\u2019uso del logo Triman<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2025\/09\/08\/propylparaben-proposta-di-classificazione\/\">Propylparaben, proposta di 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href=\"https:\/\/www.dossiermanager.it\/en\/2025\/04\/23\/sccs-presa-in-carico-della-valutazione-della-sicurezza-per-i-coloranti-basic-brown-16-e-basic-blue-99\/\">SCCS: presa in carico della valutazione della sicurezza per i coloranti BASIC BROWN 16 e BASIC BLUE 99<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2025\/03\/24\/regolamento-deforestazione-non-interessa-i-prodotti-cosmetici\/\">Regolamento Deforestazione non interessa i prodotti cosmetici<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2025\/03\/14\/preliminary-opinion-sccs-dhhb\/\">Preliminary Opinion SCCS DHHB<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2025\/03\/10\/valutazione-del-regolamento-sui-prodotti-cosmetici-invito-a-contribuire-alla-sua-valutazione\/\">Valutazione del regolamento sui prodotti cosmetici \u2013 invito a contribuire alla sua valutazione<\/a><\/li>\n<li><a 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href=\"https:\/\/www.dossiermanager.it\/en\/2024\/05\/22\/pubblicato-regolamento-1328-2024-restrizioni-su-d5e-d6\/\">Pubblicato Regolamento 1328\/2024: Restrizioni su D5e D6<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/05\/20\/opinion-preliminare-silver\/\">Opinion preliminare Silver<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/05\/17\/opinion-sccs-preliminare-sulla-tossicita-per-inalazione-dellingrediente-della-fragranza-acetylated-vetiver-oil\/\">Opinion SCCS preliminare sulla tossicit\u00e0 per inalazione dell\u2019ingrediente della fragranza Acetylated Vetiver Oil<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/05\/13\/opinion-sccs-preliminare-su-citral-metodologia-qra2-per-la-sensibilizzazione-cutanea\/\">Opinion SCCS preliminare su Citral \u2013 Metodologia QRA2 per la sensibilizzazione cutanea<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/05\/09\/opinion-sccs-triphenyl-phosphate-vetiver\/\">Opinion SCCS Triphenyl Phosphate Vetiver<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/04\/12\/nuova-regolamentazione-uk-bht-e-differenze-con-il-regolamento-europeo-1223-2009\/\">Nuova Regolamentazione UK: BHT e differenze con il Regolamento Europeo 1223\/2009<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/04\/05\/reg-2024-996-aggiornamento-ingredienti-cosmetici\/\">Reg.2024\/996 \u2013 Aggiornamento ingredienti cosmetici<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/04\/03\/divieto-di-greenwashing-regolamento-ue-2024-825\/\">Divieto di greenwashing \u2013 Regolamento UE 2024\/825<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/03\/21\/regolamento-nanomateriali\/\">Regolamento Nanomateriali<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/03\/21\/opinion-sccs-hydroxypropyl-p-phenylenediamine\/\">Opinion SCCS Hydroxypropyl p-phenylenediamine<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/03\/21\/congresso-annuale-erpa-sulle-normative-e-conformita-dei-prodotti-cosmetici\/\">Congresso Annuale ERPA sulle Normative e Conformit\u00e0 dei prodotti cosmetici<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/03\/21\/xxi-atp-e-classificazione-sostanze\/\">XXI ATP e Classificazione Sostanze<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/03\/18\/tea-tree-oil-aggiornamento-sulla-probabile-futura-classificazione\/\">Tea Tree Oil, aggiornamento sulla probabile futura classificazione<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/03\/07\/ncs-sostanze-naturali-complesse-allergeni-e-loro-gestione-in-dossier-manager\/\">NCS \u2013 Sostanze Naturali Complesse, allergeni e loro gestione in Dossier Manager<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/02\/29\/microplastiche-lineeguida-effci-cosmetics-europe\/\">Microplastiche \u2013 regolamento 2023\/2055 che modifica l\u2019allegato XVII del regolamento REACH<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/02\/19\/gpsr-e-cosmetici\/\">Vendita a distanza: regolamento GPSR e linee guida di Cosmetics Europe per i prodotti cosmetici<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/01\/12\/benzophenone-4-opinion-preliminare-sccs\/\">Benzophenone-4: Opinon preliminare SCCS<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/12\/22\/sicurezza-dellalluminio-nei-prodotti-cosmetici-sccs-preliminary-opinion-dicembre-2023-submission-iv\/\" target=\"_blank\" rel=\"noopener\">Sicurezza dell\u2019alluminio nei prodotti cosmetici \u2013 SCCS Preliminary Opinion Dicembre 2023 Submission IV<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/12\/19\/francia-e-la-legge-agec\/\" target=\"_blank\" rel=\"noopener\">Francia e la legge AGEC<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/11\/30\/corrigendum-sccs-xii\/\" target=\"_blank\" rel=\"noopener\">Corrigendum SCCS XII<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/11\/27\/aggiornamento-su-ingredienti-d4-d5-e-d6\/\" target=\"_blank\" rel=\"noopener\">Aggiornamento su ingredienti D4, D5 e D6<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/11\/20\/mocra-aggiornamento\/\">MoCRA: aggiornamento<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/11\/09\/possibili-nuove-classificazioni-cmr-per-inci-cosmetici\/\">Possibili nuove classificazioni CMR per INCI cosmetici<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/10\/23\/nuovi-allergeni-reg-2023-1545-interpretazione-e-inserimento-componenti-dellessenza-in-dossier-manager\/\" target=\"_blank\" rel=\"noopener\">Nuovi allergeni (REG. 2023\/1545): interpretazione e inserimento componenti dell\u2019essenza in Dossier ManagerMicroplastiche \u2013 Regolamento 2023\/2055 che modifica l\u2019allegato XVII del regolamento REACHVI OMNIBUS ACT, Reg. 2023-1490 aggiorna l\u2019allegato II del. Reg.1223-2009<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/10\/12\/microplastiche-regolamento-2023-2055-che-modifica-lallegato-xvii-del-regolamento-reach\/\" target=\"_blank\" rel=\"noopener\">Microplastiche \u2013 Regolamento 2023\/2055 che modifica l\u2019allegato XVII del regolamento REACHVI OMNIBUS ACT, Reg. 2023-1490 aggiorna l\u2019allegato II del. Reg.1223-2009<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/10\/09\/vi-omnibus-act-reg-2023-1490-aggiorna-lallegato-ii-del-reg-1223-2009\/\" target=\"_blank\" rel=\"noopener\">VI OMNIBUS ACT, Reg. 2023-1490 aggiorna l\u2019allegato II del. Reg.1223-2009<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/09\/11\/mocra-aggiornamenti-per-la-registrazione-dei-siti-produttivi-e-della-lista-prodotti\/\" target=\"_blank\" rel=\"noopener\">MoCRA: aggiornamenti per la registrazione dei Siti Produttivi e della lista prodotti<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/07\/31\/nuovi-allergeni-da-etichettare\/\" target=\"_blank\" rel=\"noopener\">Nuovi allergeni da etichettare<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/07\/24\/regolamento-ue-2023-988-sicurezza-prodotti\/\" target=\"_blank\" rel=\"noopener\">Regolamento (UE) 2023\/988 sicurezza prodotti<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/07\/24\/ingredienti-cosmetici-nuove-restrizioni-entro-la-fine-del-2023\/\">Ingredienti cosmetici: nuove restrizioni entro la fine del 2023<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/07\/17\/aggiornamento-microplastiche\/\">Aggiornamento microplastiche<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/07\/07\/ttc-e-ittc\/\">TTC e iTTC<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/06\/19\/interferenti-endocrini\/\">Interferenti endocrini<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/06\/14\/sccs-xii-nam-new-approach-methodology-ngra-next-generation-risk-assessment\/\">SCCS XII \u2013 NAM (New Approach Methodology) &amp; NGRA (Next Generation Risk Assessment)<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/06\/07\/bozza-regolamento-sulla-restrizione-duso-dei-nanomateriali\/\">Bozza Regolamento sulla restrizione d\u2019uso dei nanomateriali<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/05\/24\/hc-blue-18-sccs-opinion\/\">HC BLUE 18 \u2013 SCCS Opinion<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/05\/18\/sccs-xii-16-maggio-2023\/\">SCCS XII 16 Maggio 2023<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/05\/10\/classificazione-sostanze-xviii-atp-omnibus-act-vi-nuova-data-entrata-in-vigore\/\">Classificazione Sostanze, XVIII ATP, Omnibus Act VI \u2013 Nuova data entrata in vigore<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/05\/08\/test-preliminare-tinture-per-capelli-raccomandazione-ce-n-27-del-26-04-2023\/\">Test preliminare tinture per capelli \u2013 Raccomandazione CE N.27 del 26\/04\/2023<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/04\/17\/aggiornamento-mocra\/\">Aggiornamento MoCRA e nuovo portale registrazione prodotti e siti produttivi<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/03\/15\/sccs-1648-22-preliminary-opinion-hydroxyapatite-nano\/\">SCCS\/1648\/22: Preliminary Opinion Hydroxyapatite (nano)<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/02\/16\/fdora-e-mocra-aggiornamenti-normativi-per-gli-stati-uniti-damerica\/\">FDORA 2022 e il Modernization of Cosmetics Regulation Act: aggiornamenti normativi per gli Stati Uniti d\u2019America<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2022\/12\/29\/retinol\/\">Retinol<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2022\/12\/19\/nuova-opinion-sccs-triclosan-e-triclocarban\/\">Nuova Opinion SCCS: Triclosan e Triclocarban<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2022\/12\/13\/titanium-dioxide\/\">Titanium Dioxide<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2022\/12\/05\/aggiornamento-su-ingredienti-bhthomosalate-resorcinol-acid-yellow-3-haa229\/\">Aggiornamento ingredienti: BHT,Homosalate, Resorcinol, Acid yellow 3, HAA229<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2022\/11\/03\/omnibus-act-v-definitivo\/\">Omnibus Act V definitivo<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2022\/10\/17\/etichette-cosmetici-nuovi-allergeni-da-dichiarare\/\">Etichette cosmetici: nuovi allergeni da dichiarare<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2022\/07\/27\/aggiornamento-allegato-v-al-reg-1223-2009-i-conservanti-cessori-di-formaldeide\/\">Aggiornamento allegato V al Reg.1223-2009: i conservanti cessori di formaldeide<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2022\/06\/17\/nuovo-modulo-per-la-comunicazione-delle-informazioni-sui-siti-di-produzione-dei-cosmetici\/\">Nuovo modulo per la comunicazione delle informazioni sui siti di produzione dei cosmetici<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2022\/05\/27\/dihydroxyacetone\/\">DIHYDROXYACETONE<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2022\/05\/25\/4-methylbenzylidene-camphor-4-mbc\/\">4-Methylbenzylidene camphor (4-MBC) e nuove restrizioni entro la fine dell\u2019anno<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2022\/05\/17\/classificazione-sostanze-xviii-atp\/\">Classificazione sostanze, XVIII ATP<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2022\/05\/10\/omnibus-act-v-xvii-atp\/\">Ominbus Act V-XVII ATP<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2022\/03\/24\/opinion-sccs-kojic-acid-17-marzo\/\">Opinion SCCS Kojic Acid 17 marzo<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2022\/03\/11\/nuova-restrizione-in-allegato-iii-regolamento-ue-2022-135-della-commissione-del-31-gennaio-2022\/\">NUOVA RESTRIZIONE IN ALLEGATO III: regolamento (UE) 2022\/135 della commissione del 31 gennaio 2022<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2022\/01\/04\/omnibus-act-iv\/\">Omnibus Act IV<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2021\/11\/09\/allergeni-nelle-fragranze-ultime-novita-di-etichettatura-per-i-prodotti-cosmetici-2\/\">ALLERGENI nelle fragranze, ultime NOVIT\u00c0 di etichettatura per i prodotti cosmetici<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2021\/06\/25\/classificazione-sostanze-xvii-atp\/\">Classificazione sostanze, XVII ATP<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2021\/06\/15\/omnibus-act-iii\/\">Omnibus Act III<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2021\/05\/31\/sccs-xi-revisione-del-rischio-inalatorio\/\">SCCS XI: Revisione del rischio inalatorio<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2021\/05\/31\/sccs-xi-tutte-le-novita-salienti-della-undicesima-revisione-delle-linee-guida-per-la-valutazione-della-sicurezza-degli-ingredienti-cosmetici\/\">SCCS XI: tutte le novit\u00e0 salienti della undicesima revisione delle linee guida per la valutazione della sicurezza degli ingredienti cosmetici<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2021\/05\/09\/archivio-preparati-pericolosi-disattivazione-caricamento-massivo-di-notifiche-il-20-maggio-2021\/\">Archivio Preparati Pericolosi: disattivazione caricamento massivo di notifiche il 20 maggio 2021<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2021\/03\/26\/allergeni-nelle-fragranze-ultime-novita-di-etichettatura-per-i-prodotti-cosmetici\/\">ALLERGENI nelle fragranze, ultime NOVITA\u2019 di etichettatura per i prodotti cosmetici<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2021\/01\/21\/etichettatura-allergeni-cosa-ci-dovremo-aspettare\/\">Allergen labeling: what to expect<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2020\/12\/14\/dettagli-aggiornamento-7-3-0-1\/\">Technical-Normative Update Details<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2020\/11\/20\/la-banca-dati-scip-per-articoli-con-sostanze-svhc\/\">The SCIP database for articles with SVHC substances<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2020\/09\/17\/classificazione-sostanze-anticipazione-omnibus-2021\/\">Classificazione sostanze, anticipazione Omnibus Act 2021<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2020\/07\/15\/aggiornamenti-su-zinc-pyrithione-titanium-dioxide-e-resorcinol\/\">Aggiornamneti su ZINC PYRITHIONE, TITANIUM DIOXIDE e RESORCINOL<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2020\/07\/03\/lilial-vietato-allinterno-dei-prodotti-cosmetici\/\">Lilial vietato all\u2019interno dei prodotti cosmetici<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2020\/06\/22\/la-teofillina-esercita-effetti-anti-eta-e-anti-citotossicita-sulla-pelle-umana-ex-vivo\/\">Theophylline exerts anti-aging and anti-cytotoxicity effects on human skin ex vivo<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2020\/04\/16\/coloranti-per-capelli-ad-ossidazione-e-non-ultime-novita-e-qualche-riepilogo\/\">Hair colorants, oxidation and not, the latest news and some summary<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2020\/04\/09\/aggiornamenti-normativi-sccs-alluminio-final-opinion\/\">SCCS Aluminum Regulatory Updates Final Opinion<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2020\/02\/28\/titanium-dioxide-e-titanium-dioxidenano-ultime-novita-e-qualche-riepilogo\/\">TITANIUM DIOXIDE and TITANIUM DIOXIDE(NANO), last news and some summary<\/a><\/li>\n<li class=\"entry-title fusion-responsive-typography-calculated\" data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2020\/02\/21\/anticipazioni-sullomnibus-act-2020-analisi-allergene\/\">Anticipazioni sull\u2019Omnibus act 2020 \u2013 analisi allergene<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2020\/03\/10\/business-as-usual-adempimenti-dpcm-08-03-2020\/\">Business As Usual \u2013 Adempimenti DPCM 08\/03\/202<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2020\/03\/27\/zinc-pyrithione-ultime-novita-e-qualche-riepilogo\/\">ZINC PYRITHIONE, latest news and a summary<\/a><\/li>\n<\/ul>\n<\/div><\/div><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs nav-justified\" role=\"tablist\" aria-orientation=\"horizontal\"><li  role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-c65f104e9c46d3ad741\" aria-selected=\"false\" tabindex=\"-1\" id=\"mobile-fusion-tab-c65f104e9c46d3ad741\" href=\"#tab-c65f104e9c46d3ad741\"><h4 class=\"fusion-tab-heading\">Tutorial<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-pane fade fusion-clearfix\" role=\"tabpanel\" tabindex=\"0\" aria-labelledby=\"fusion-tab-c65f104e9c46d3ad741\" id=\"tab-c65f104e9c46d3ad741\"><div class=\"awb-tab-pane-inner\">\n<ul>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2025\/09\/09\/come-aggiornare-il-proprio-dossier-manager\/\">Come aggiornare il proprio Dossier Manager<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/06\/01\/come-disattivare-unutenza\/\">Come disattivare un\u2019utenza<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/03\/27\/la-nuova-formula-quali-quantitativa\/\">The new Quali-Quantitative formula<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2022\/10\/25\/sostanze-tecniche-e-impurezze\/\">Sostanze Tecniche e Impurezze<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2022\/09\/23\/come-esportare-una-formula-distinta-base\/\">Come esportare una formula distinta base<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2022\/09\/23\/come-eliminare-un-articolo-con-pif-formule-e-versioni-di-specifica-associate\/\">Come eliminare un articolo con PIF, formule e versioni di specifica associate<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2022\/02\/23\/come-esportare-letichetta-di-un-prodotto\/\">Come esportare l\u2019etichetta di un prodotto<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2022\/01\/26\/generazione-blacklist-da-modelli\/\">Generazione blacklist da modelli<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2021\/07\/30\/come-modificare-lassorbimento-in-percentuale-del-tuo-prodotto\/\">Come modificare l\u2019assorbimento in percentuale del tuo prodotto<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2020\/08\/04\/come-calcolare-il-sed-con-categorie-cosmetiche-personalizzate\/\">How to calculate the SED with customized cosmetic categories<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2021\/12\/21\/modulo-per-letichettatura-ambientale-degli-imballaggi\/\">Modulo per l\u2019Etichettatura Ambientale degli Imballaggi<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2020\/07\/23\/come-inserire-dati-nelle-categorie-cosmetiche-per-il-calcolo-qta10\/\">How to enter data in cosmetic categories for QTA10 calculation<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2020\/05\/21\/come-inserire-i-dati-tossicologici\/\">How to enter toxicology data<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2020\/05\/11\/come-gestire-gli-allergeni-in-etichetta\/\">How to handle allergens on the label<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2020\/03\/19\/le-categorie-cosmetiche-strategie-di-selezione-e-come-crearne-di-nuove\/\">Le categorie cosmetiche, strategie di selezione e come crearne di nuove<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2020\/03\/03\/contratto-di-manutenzione\/\">How to find the Maintenance Agreement, User License and active modules<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2020\/02\/17\/come-gestire-le-note-predefinite-del-pif\/\">Come gestire le note predefinite del PIF<\/a><\/li>\n<\/ul>\n<\/div><\/div><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs nav-justified\" role=\"tablist\" aria-orientation=\"horizontal\"><li  role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-afa7445234f2cecb6b7\" aria-selected=\"false\" tabindex=\"-1\" id=\"mobile-fusion-tab-afa7445234f2cecb6b7\" href=\"#tab-afa7445234f2cecb6b7\"><h4 class=\"fusion-tab-heading\">Regulatory Answers<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-pane fade fusion-clearfix\" role=\"tabpanel\" tabindex=\"0\" aria-labelledby=\"fusion-tab-afa7445234f2cecb6b7\" id=\"tab-afa7445234f2cecb6b7\"><div class=\"awb-tab-pane-inner\">\n<ul>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2025\/07\/14\/esposizione-inalatoria-nei-cosmetici-come-calcolarla-correttamente-secondo-sccs-xi\/\">Esposizione inalatoria nei cosmetici: come calcolarla correttamente secondo SCCS XI?<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/03\/25\/ho-scaricato-laggiornamento-tecnico-normativo-ma-non-vedo-le-modifiche-applicate\/\">Ho scaricato l\u2019aggiornamento Tecnico Normativo ma non vedo le modifiche applicate<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/03\/25\/e-possibile-ottenere-da-dossier-manager-un-avviso-sulleventuale-superamento-della-soglia-di-utilizzo-prevista-per-gli-inci-contenuti-in-allegato-iii\/\">Avviso sul superamento della soglia di utilizzo prevista per gli INCI contenuti in Allegato III?<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/02\/20\/quali-sono-le-fonti-dei-nostri-aggiornamenti-tecnico-normativi\/\">Quali sono le fonti dei nostri aggiornamenti Tecnico \u2013 Normativi?<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/02\/02\/i-nuovi-allergeni-e-la-loro-gestione-in-dossier-manager-il-regolamento-ue-2023-1545\/\">I nuovi allergeni e la loro gestione in Dossier Manager \u2013 il regolamento UE 2023\/1545<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2022\/09\/28\/cosmetici-per-bambini-e-neonati-e-necessario-considerare-un-mos-specifico\/\">Cosmetici per bambini e neonati: \u00e8 necessario considerare un MOS specifico?<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2022\/05\/11\/come-fare-il-pif-di-un-prodotto-costituito-da-piu-prodotti\/\">Come fare il PIF di un prodotto costituito da pi\u00f9 prodotti<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2021\/07\/30\/come-modificare-lassorbimento-in-percentuale-del-tuo-prodotto\/\">Come modificare l\u2019assorbimento in percentuale del tuo prodotto<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2021\/07\/30\/come-calcolare-il-sed-inalatorio-di-tipo-2-del-tuo-prodotto\/\">Come calcolare il SED inalatorio di tipo 2 del tuo prodotto<\/a><\/li>\n<li><a href=\"https:\/\/www.dossiermanager.it\/en\/2021\/07\/29\/come-calcolare-il-sed-inalatorio-di-tipo-1-del-tuo-prodotto\/\">Come calcolare il SED inalatorio di tipo 1 del tuo prodotto<\/a><\/li>\n<\/ul>\n<\/div><\/div><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs nav-justified\" role=\"tablist\" aria-orientation=\"horizontal\"><li  role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-034ebdb30b6509ab6da\" aria-selected=\"false\" tabindex=\"-1\" id=\"mobile-fusion-tab-034ebdb30b6509ab6da\" href=\"#tab-034ebdb30b6509ab6da\"><h4 class=\"fusion-tab-heading\">Release Notes<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-pane fade fusion-clearfix\" role=\"tabpanel\" tabindex=\"0\" aria-labelledby=\"fusion-tab-034ebdb30b6509ab6da\" id=\"tab-034ebdb30b6509ab6da\"><div class=\"awb-tab-pane-inner\">\n<ul>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2026\/09\/03\/dossier-manager-8-7-9-0\/\">Dossier Manager 8.7.9.0<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2026\/04\/24\/dossier-manager-8-7-1\/\">Dossier Manager 8.7.1<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2025\/07\/25\/dossier-manager-8-7\/\">Dossier Manager 8.7<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2025\/02\/04\/dossier-manager-8-6-7-0\/\">Dossier Manager 8.6.7<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/07\/17\/dossier-manager-8-6-4-0\/\">Dossier Manager 8.6.4<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/03\/17\/dossier-manager-8-6\/\">Dossier Manager 8.6<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/12\/05\/dossier-manager-8-5-2\/\">Dossier Manager 8.5.2<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/09\/20\/dossier-manager-8-1-5-2\/\">Dossier Manager 8.1.5.2<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/05\/31\/dossier-manager-8-1-5\/\">Dossier Manager 8.1.5<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/02\/22\/dossier-manager-8-1-2\/\">Dossier Manager 8.1.2<\/a><\/li>\n<li class=\"entry-title fusion-responsive-typography-calculated\" data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2021\/12\/14\/dossier-manager-8\/\">Dossier Manager 8<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2021\/07\/28\/dossier-manager-7-4\/\">Dossier Manager 7.4<\/a><\/li>\n<li class=\"entry-title fusion-responsive-typography-calculated\" data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2021\/07\/06\/release-7-3-6-aggiornamento-obbligatorio-del-servizio-di-teleassistenza\/\">Release 7.3.6: aggiornamento obbligatorio per il servizio di teleassistenza HelpDesk<\/a><\/li>\n<li class=\"entry-title fusion-responsive-typography-calculated\" data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2021\/05\/20\/traduzioni-automatiche-aggiorna-dm-alla-7-3-5\/\">Traduzioni automatiche: aggiorna DM alla 7.3.5<\/a><\/li>\n<li class=\"entry-title fusion-responsive-typography-calculated\" data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2020\/11\/06\/le-nuove-feature-di-dossier-manager-7-3\/\">Le nuove feature di Dossier Manager 7.3<\/a><\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div>\n<div class=\"fusion-tabs fusion-tabs-2 classic nav-is-justified awb-tabs-transition awb-tabs-transition-fade horizontal-tabs icon-position-left mobile-mode-accordion\" style=\"--awb-title-border-radius-top-left:0px;--awb-title-border-radius-top-right:0px;--awb-title-border-radius-bottom-right:0px;--awb-title-border-radius-bottom-left:0px;--awb-inactive-color:#ebeaea;--awb-background-color:#ffffff;--awb-border-color:#ebeaea;--awb-active-border-color:#a5363c;--awb-active-border-size:3px;--awb-transition-speed:300ms;--awb-border-size:1px;\"><div class=\"nav\"><ul class=\"nav-tabs nav-justified\" role=\"tablist\" aria-orientation=\"horizontal\"><li class=\"active\" role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-936a3fdf32ea282f30d\" aria-selected=\"true\" tabindex=\"0\" id=\"fusion-tab-936a3fdf32ea282f30d\" href=\"#tab-936a3fdf32ea282f30d\"><h4 class=\"fusion-tab-heading\">News<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-content\"><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs nav-justified\" role=\"tablist\" aria-orientation=\"horizontal\"><li class=\"active\" role=\"presentation\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-936a3fdf32ea282f30d\" aria-selected=\"true\" tabindex=\"0\" id=\"mobile-fusion-tab-936a3fdf32ea282f30d\" href=\"#tab-936a3fdf32ea282f30d\"><h4 class=\"fusion-tab-heading\">News<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-pane fade fusion-clearfix in active\" role=\"tabpanel\" tabindex=\"0\" aria-labelledby=\"fusion-tab-936a3fdf32ea282f30d\" id=\"tab-936a3fdf32ea282f30d\"><div class=\"awb-tab-pane-inner\">\n<ul>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2025\/11\/25\/progetto-accademia-d-lab-its-crema-nuove-tecnologie-della-vita-2025\/\">Progetto Accademia: D-LAB @ ITS Crema Nuove Tecnologie della Vita 2025<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2025\/11\/06\/giornata-dapprofondimento-regulatory-dossier-manager-edizione-2025\/\">Giornata d\u2019Approfondimento Regulatory Dossier Manager \u2013 Edizione 2025<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2025\/09\/25\/aggiornamento-del-manuale-dei-cosmetici-borderline-v-5-5\/\">Aggiornamento del Manuale dei cosmetici Borderline: v.5.5<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2025\/07\/11\/progetto-accademia-dossier-manager-its-nuove-tecnologie-della-vita-2025\/\">Progetto Accademia: Dossier Manager @ ITS Nuove Tecnologie della Vita 2025<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2025\/05\/13\/giornata-regulatory-dossier-manager-il-valore-di-un-confronto-tra-professionisti\/\">Giornata Regulatory Dossier Manager: il valore di un confronto tra professionisti<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2025\/03\/14\/progetto-accademia-dossier-manager-universita-durbino\/\">Progetto Accademia: Dossier Manager @ Universit\u00e0 d\u2019Urbino<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2025\/03\/06\/perche-non-affidarsi-esclusivamente-a-sistemi-automatizzati-nella-valutazione-regolatoria\/\">Perch\u00e9 non affidarsi esclusivamente a sistemi automatizzati nella valutazione regolatoria<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2025\/01\/14\/la-scelta-del-point-of-departure-pod-noael-vs-bmd-nella-valutazione-della-sicurezza\/\">La Scelta del Point of Departure (PoD): NOAEL vs. BMD nella Valutazione della Sicurezza<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/10\/14\/progetto-accademia-dossier-manager-its-nuove-tecnologie-della-vita\/\">Progetto Accademia: Dossier Manager @ ITS Nuove Tecnologie della Vita<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/05\/22\/dossier-manager-partecipa-alla-terza-edizione-di-itdevcon-spring-edition\/\">Dossier Manager partecipa alla terza edizione di ITDevCon Spring Edition<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/03\/07\/la-casa-bianca-esorta-gli-sviluppatori-a-utilizzare-linguaggi-di-programmazione-memory-safe-come-delphi\/\">La Casa Bianca esorta gli sviluppatori a utilizzare linguaggi di programmazione \u201cmemory-safe\u201d come Delphi<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/03\/28\/registrazione-webinar-la-gestione-allergeni-in-dossier-manager\/\">Registrazione webinar \u2013 La gestione allergeni in Dossier Manager<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/01\/15\/richiedi-la-tua-attivita-tecnica-gratuita-per-il-passaggio-a-docudocs\/\">Request your free technical analysis for the transition to DocuDocs<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2024\/01\/07\/adeguamento-istat-canoni-di-manutenzione\/\">Adeguamento ISTAT canoni di manutenzione<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/07\/10\/docudocs-e-plus\/\">Dossier Manager becomes Dossier Manager Plus<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2023\/03\/27\/la-nuova-formula-quali-quantitativa\/\">The new Quali-Quantitative formula<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2022\/10\/25\/sostanze-tecniche-e-impurezze\/\">Sostanze Tecniche e Impurezze<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2021\/12\/21\/modulo-per-letichettatura-ambientale-degli-imballaggi\/\">Modulo per l\u2019Etichettatura Ambientale degli Imballaggi<\/a><\/li>\n<li class=\"entry-title fusion-responsive-typography-calculated\" data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2021\/07\/14\/dossier-manager-alluniversita-di-pavia\/\">Dossier Manager all\u2019Universit\u00e0 di Pavia<\/a><\/li>\n<li data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2021\/08\/05\/offerta-estiva-utilizza-dossier-manager-anche-in-smart-working\/\">Offerta estiva, utilizza Dossier Manager anche in smart working<\/a><\/li>\n<li class=\"entry-title fusion-responsive-typography-calculated\" data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2021\/03\/22\/risolvi-i-tuoi-problemi-brexit\/\">Risolvi i tuoi problemi Brexit<\/a><\/li>\n<li class=\"entry-title fusion-responsive-typography-calculated\" data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2020\/10\/15\/che-cose-il-terminal-server-e-come-funziona\/\">What is the Terminal Server and how does it work?<\/a><\/li>\n<li class=\"entry-title fusion-responsive-typography-calculated\" data-fontsize=\"65\" data-lineheight=\"71.5px\"><a href=\"https:\/\/www.dossiermanager.it\/en\/2020\/10\/15\/i-vantaggi-di-una-licenza-floating\/\">The advantages of Dossier Manager with a Floating license<\/a><\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div>\n<div class=\"fusion-clearfix\"><\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[17],"tags":[],"class_list":["post-778","post","type-post","status-publish","format-standard","hentry","category-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>TITANIUM DIOXIDE e TITANIUM DIOXIDE(NANO), ultime novit\u00e0 e qualche riepilogo - Dossier Manager<\/title>\n<meta name=\"robots\" content=\"noindex, follow\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"TITANIUM DIOXIDE e TITANIUM DIOXIDE(NANO), ultime novit\u00e0 e qualche riepilogo - Dossier Manager\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.dossiermanager.it\/en\/2020\/02\/28\/titanium-dioxide-e-titanium-dioxidenano-ultime-novita-e-qualche-riepilogo\/\" \/>\n<meta property=\"og:site_name\" content=\"Dossier Manager\" \/>\n<meta property=\"article:published_time\" content=\"2020-02-28T15:09:51+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-11-12T10:20:00+00:00\" \/>\n<meta name=\"author\" content=\"INT.E.G.RA.\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@wp_247071\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"INT.E.G.RA.\" \/>\n\t<meta name=\"twitter:label2\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"10 minutes\" \/>\n<script type=\"application\/ld+json\" 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