The pilot study "Theophylline exerts complex anti-ageing and anti-cytotoxicity effects in human skin ex vivo" (International Journal of Cosmetic Science, 42, 79-88) shows that theophylline possesses several complex anti-ageing and antioxidant properties to protect human skin.

Theophylline is a phosphodiesterase inhibitor clinically used as a therapeutic for the treatment of asthma.

This study encourages further examination of theophylline as a candidate for anti-aging treatment.